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Rabbit anti-ACCN1 polyclonal antibody - middle region
Catalog Number:OM107366
OM107366
Discount Price
OM107366-100ul
1~2 Week
100ul
OM107366-50ul
50ul
OM107366-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-ACCN1 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias ACCN, ASIC2, ASIC2a, BNC1, BNaC1, MDEG, hBNaC1, ACCN1
Immunogen The immunogen for anti-ACCN1 antibody: synthetic peptide directed towards the middle region of human ACCN1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineHorseHumanMouseRabbitRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ACCN1
Gene Synonyms ACCN
ASIC2
ASIC2a
BNC1
BNaC1
MDEG
hBNaC1
ACCN1
Gene Full Name Acid-sensing (proton-gated) ion channel 2
Gene Summary ACCN1 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.
Alternative Names ACCN
ASIC2
ASIC2a
BNC1
BNaC1
MDEG
hBNaC1
ACCN1
Molecular Weight(MW) 58kDa
Sequence 512 amino acids
Database Links
Entrez Gene 40
SwissProt ID Q16515
Protein Accession NP_001085
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: THP-1 cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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