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Rabbit anti-ZIC2 polyclonal antibody - C-terminal region

Catalog Number:OM107501
OM107501
Discount Price
OM107501-100ul
1~2 Week
100ul
OM107501-50ul
50ul
OM107501-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-ZIC2 polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Antigen Alias HPE5
Immunogen The immunogen for anti-ZIC2 antibody: synthetic peptide directed towards the C terminal of human ZIC2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity HumanPig
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ZIC2
Gene Synonyms HPE5
Gene Full Name Zic family member 2
Gene Summary ZIC2 is a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects.This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.
Alternative Names HPE5
Molecular Weight(MW) 55kDa
Sequence 532 amino acids
Database Links
Entrez Gene 7546
SwissProt ID O95409
Protein Accession NP_009060
Application

Western blot

0.2-1 ug/mlPositive Control: HepG2 cell lysate

Western blot

0.2-1 ug/mlPositive Control: HepG2 cell lysate
Application Notes WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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