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Rabbit anti-MCM8 polyclonal antibody - N-terminal region

Catalog Number:OM107941
OM107941
Discount Price
OM107941-100ul
1~2 Week
100ul
OM107941-50ul
50ul
OM107941-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-MCM8 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias C20orf154, MGC119522, MGC119523, MGC12866, MGC4816, REC, dJ967N21.5
Immunogen The immunogen for anti-MCM8 antibody: synthetic peptide directed towards the N terminal of human MCM8
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHorseHumanMousePigRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol MCM8
Gene Synonyms C20orf154
MGC119522
MGC119523
MGC12866
MGC4816
REC
dJ967N21.5
Gene Full Name Minichromosome maintenance complex component 8
Gene Summary This protein is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alternative Names C20orf154
MGC119522
MGC119523
MGC12866
MGC4816
REC
dJ967N21.5
Molecular Weight(MW) 94kDa
Sequence 840 amino acids
Database Links
Entrez Gene 84515
SwissProt ID Q9UJA3
Protein Accession NP_115874
Application

Western blot

MCM8 WB Sample: siRNA Mock and siRNA MCM8 Dilution 1:1000

Western blot

0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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