Western blot
1.25ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate| Product Name | Rabbit anti-RUNX2 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CCD, AML3, CCD1, OSF2, CBFA1, OSF-2, PEA2aA, PEBP2A1, PEBP2A2, PEBP2aA, PEBP2aA1 |
| Immunogen | The immunogen for anti-RUNX2 antibody: synthetic peptide directed towards the middle region of human RUNX2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | RUNX2 |
|---|---|
| Gene Synonyms | CCD AML3 CCD1 OSF2 CBFA1 OSF-2 PEA2aA PEBP2A1 PEBP2A2 PEBP2aA PEBP2aA1 |
| Gene Full Name | Runt-related transcription factor 2 |
| Gene Summary | RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing. |
| Alternative Names | CCD AML3 CCD1 OSF2 CBFA1 OSF-2 PEA2aA PEBP2A1 PEBP2A2 PEBP2aA PEBP2aA1 |
| Molecular Weight(MW) | 57kDa |
| Sequence | 521 amino acids |
| Entrez Gene | 860 |
|---|---|
| SwissProt ID | Q13950 |
| Protein Accession | NP_001019801 |
Western blot
1.25ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
