Western blot
Lane 1: 20ug mouse mesenchymal stem cell lysate Primary Antibody Dilution :Western blot
0.2-1 ug/ml| Product Name | RUNX2 antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-RUNX2 antibody: synthetic peptide directed towards the C terminal of human RUNX2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Bovine,Dog,Guinea Pig,Horse,Human,Mouse,Pig,Rat,Zebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RUNX2 |
|---|---|
| Gene Synonyms | AML3 CBFA1 CCD CCD1 MGC120022 MGC120023 OSF2 PEA2aA PEBP2A1 PEBP2A2 PEBP2aA PEBP2aA1 OSF-2 |
| Gene Full Name | Runt-related transcription factor 2 |
| Gene Summary | RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing.This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. |
| Alternative Names | AML3 CBFA1 CCD CCD1 MGC120022 MGC120023 OSF2 PEA2aA PEBP2A1 PEBP2A2 PEBP2aA PEBP2aA1 OSF-2 |
| Molecular Weight(MW) | 55kDa |
| Sequence | 507 amino acids |
Western blot
Lane 1: 20ug mouse mesenchymal stem cell lysate Primary Antibody Dilution :
Western blot
0.2-1 ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
