Western blot
Host: Rabbit Target Name: Figla Sample Tissue: Mouse Spleen lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-Figla Antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | bHLHc8 |
| Immunogen | The immunogen for Anti-Figla antibody is: synthetic peptide directed towards the C-terminal region of Mouse Figla |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | MouseHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Figla |
|---|---|
| Gene Synonyms | bHLHc8 |
| Gene Full Name | folliculogenesis specific basic helix-loop-helix |
| Gene Summary | Figla is a germ-line specific transcription factor implicated in postnatal oocyte-specific gene expression. It plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. It is essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Figla binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters. |
| Alternative Names | bHLHc8 |
| Molecular Weight(MW) | 21kDa |
| Sequence | 194 amino acids |
Western blot
Host: Rabbit Target Name: Figla Sample Tissue: Mouse Spleen lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
