Western blot
Host: Rabbit Target Name: Runx1 Sample Tissue: Mouse Skeletal Muscle lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-Runx1 Antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AI462102, AML1, Cbfa2, Pebp2a2, Pebpa2b |
| Immunogen | The immunogen for Anti-Runx1 antibody is: synthetic peptide directed towards the N-terminal region of MOUSE Runx1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | MouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Runx1 |
|---|---|
| Gene Synonyms | AI462102 AML1 Cbfa2 Pebp2a2 Pebpa2b |
| Gene Full Name | runt related transcription factor 1 |
| Gene Summary | CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. Runx1 is essential for the development of normal hematopoiesis. Isoform 4 shows higher binding activities for target genes and binds TCR-beta-E2 and RAG-1 target site with threefold higher affinity than other isoforms. It is less effective in the context of neutrophil terminal differentiation. Runx1 acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the BLK promoter. It inhibits KAT6B-dependent transcriptional activation . |
| Alternative Names | AI462102 AML1 Cbfa2 Pebp2a2 Pebpa2b |
| Molecular Weight(MW) | 42kDa |
| Sequence | 387 amino acids |
Western blot
Host: Rabbit Target Name: Runx1 Sample Tissue: Mouse Skeletal Muscle lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
