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Rabbit anti-EGR4 polyclonal antibody - C-terminal region

Catalog Number:OM108549
OM108549
Discount Price
OM108549-100ul
1~2 Week
100ul
OM108549-50ul
50ul
OM108549-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-EGR4 polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Antigen Alias NGFIC, NGFI-C, PAT133
Immunogen The immunogen for anti-EGR4 antibody: synthetic peptide directed towards the C terminal of human EGR4
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol EGR4
Gene Synonyms NGFIC
NGFI-C
PAT133
Gene Full Name Early growth response 4
Gene Summary The nerve growth factor-induced clone C (NGFI-C/EGR4) gene is a zinc-finger transcription factor that is rapidly induced by nerve growth factor in rat pheochromocytoma PC12 cells and by seizure in brain. NGFI-C/EGR4 is closely related to the previously described early response genes, nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR-4 functionally cooperate with NFAT proteins and induce expression of IL-2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
Alternative Names NGFIC
NGFI-C
PAT133
Molecular Weight(MW) 51kDa
Sequence 486 amino acids
Database Links
Entrez Gene 1961
SwissProt ID Q05215
Protein Accession NP_001956
Application

Western blot

0.0625ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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