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SMARCE1 antibody - N-terminal region

Catalog Number:OM108634
OM108634
Discount Price
OM108634-100ul
1~2 Week
100ul
OM108634-50ul
50ul
OM108634-20ul
20ul
1~2 Week
Product Profile
Product Name SMARCE1 antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-SMARCE1 antibody: synthetic peptide directed towards the N terminal of human SMARCE1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB,IHC
Species Reactivity Bovine,Dog,Guinea Pig,Horse,Human,Mouse,Pig,Rat,Zebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol SMARCE1
Gene Synonyms BAF57
Gene Full Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Gene Summary SMARCE1 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
Alternative Names BAF57
Molecular Weight(MW) 47kDa
Sequence 411 amino acids
Database Links
Entrez Gene 6605
SwissProt ID Q969G3
Protein Accession NP_003070
Application

Western blot

0.2-1 ug/ml
Positive Control: Jurkat cell lysate

Immunohistochemical

Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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