Western blot
RCAN1 antibody - middle region validated by WB using MOUSE OSTEOCLASTS at 1:1000.Western blot
Positive Control: Lane 1: 20ug Wild type mouse, left ventricleWestern blot
RCAN1 antibody - middle region validated by WB using Mouse Brain at 1:500.| Product Name | RCAN1 antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-RCAN1 antibody: synthetic peptide directed towards the middle region of human RCAN1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Bovine,Dog,Human,Mouse,Pig,Rat,Sheep |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RCAN1 |
|---|---|
| Gene Synonyms | ADAPT78 CSP1 DSC1 DSCR1 MCIP1 RCN1 |
| Gene Full Name | Regulator of calcineurin 1 |
| Gene Summary | RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. |
| Alternative Names | ADAPT78 CSP1 DSC1 DSCR1 MCIP1 RCN1 |
| Molecular Weight(MW) | 28kDa |
| Sequence | 252 amino acids |
Western blot
RCAN1 antibody - middle region validated by WB using MOUSE OSTEOCLASTS at 1:1000.
Western blot
Positive Control: Lane 1: 20ug Wild type mouse, left ventricle
Western blot
RCAN1 antibody - middle region validated by WB using Mouse Brain at 1:500.| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
