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ETS2 antibody - middle region

Catalog Number:OM108830
OM108830
Discount Price
OM108830-100ul
1~2 Week
100ul
OM108830-50ul
50ul
OM108830-20ul
20ul
1~2 Week
Product Profile
Product Name ETS2 antibody - middle region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-ETS2 antibody: synthetic peptide directed towards the middle region of human ETS2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
Species Reactivity Bovine,Dog,Guinea Pig,Horse,Human,Mouse,Pig,Rabbit,Rat,Zebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ETS2
Gene Synonyms ETS2IT1
Gene Full Name V-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
Gene Summary ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names ETS2IT1
Molecular Weight(MW) 53kDa
Sequence 469 amino acids
Database Links
Entrez Gene 2114
SwissProt ID P15036
Protein Accession NP_005230
Application

Western blot

Host: Rabbit
Target Name: ETS2
Sample Tissue: Hela
Antibody Dilution: 1.0ug/ml

Western blot

ETS2 antibody - middle region validated by WB using human LCL and mouse brains at 1:1000.

Western blot

Host: Rabbit
Target Name: ETS2
Sample Tissue: Jurkat
Antibody Dilution: 1.0ug/ml
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
validation
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