Application
Antibody used in WB on human LCL, mouse brains at 1:1000.Application
Antibody used in WB on Human kidney at 0.2-1 ug/ml.| Product Name | ETS2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).1) Ge, Y., (2008) Leukemia 22 (3), 521-529 . |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ETS2. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISA,WB |
| ETS2 antibody can be used for detection of ETS2 by ELISA at 1:312500. ETS2 antibody can be used for detection of ETS2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | Drosophila,Human,Mouse,Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ETS2 |
|---|---|
| Alternative Names | ETS2 ETS2IT1 |
| Molecular Weight(MW) | 53 kDa |
Application
Antibody used in WB on human LCL, mouse brains at 1:1000.
Application
Antibody used in WB on Human kidney at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. XBL-10408 - Fetal Kidney Tissue Lysate |
|---|---|
| Application Notes | ETS2 antibody can be used for detection of ETS2 by ELISA at 1:312500. ETS2 antibody can be used for detection of ETS2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store ETS2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
