Application
WB Suggested Anti-AHRR Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysateWB
Abundances of proteins (AHR, AHRR, ARNT, and CYP1A1) in pTr2 cells determined by Western blot analysis. Cells were treated with 40 μM, 500 μM and 1000 μM Trp, respectively.WB
Abundances of proteins (AHR, AHRR, ARNT, and CYP1A1) in pTr2 cells determined by Western blot analysis. Cells were treated with 40 μM Trp (CON), CON + 10 μM CH-223191, 1000 μM Trp and 1000 μM Trp +10 μM CH-223191, respectively. Previous| Product Name | Rabbit anti-AHRR polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-AHRR antibody: synthetic peptide directed towards the middle region of human AHRR |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | DogGuinea PigHorseHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | AHRR |
|---|---|
| Gene Synonyms | AHRR |
| Gene Full Name | Aryl-hydrocarbon receptor repressor |
| Gene Summary | Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. AHRR represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, AHRR can bind to nuclear factor kappa-B.Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. The protein encoded by this gene represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, the encoded protein can bind to nuclear factor kappa-B. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Alternative Names | AHH AHHR KIAA1234 MGC167813 MGC176630 bHLHe77 |
| Molecular Weight(MW) | 78kDa |
| Sequence | 719 amino acids |
Application
WB Suggested Anti-AHRR Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate
WB
Abundances of proteins (AHR, AHRR, ARNT, and CYP1A1) in pTr2 cells determined by Western blot analysis. Cells were treated with 40 μM, 500 μM and 1000 μM Trp, respectively.
WB
Abundances of proteins (AHR, AHRR, ARNT, and CYP1A1) in pTr2 cells determined by Western blot analysis. Cells were treated with 40 μM Trp (CON), CON + 10 μM CH-223191, 1000 μM Trp and 1000 μM Trp +10 μM CH-223191, respectively. Previous| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
