| Product Name | Rabbit anti-Klhl12 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C3ip1, MGC93127 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanPigRabbitRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Klhl12 |
|---|---|
| Gene Synonyms | C3ip1 MGC93127 |
| Gene Full Name | Kelch-like 12 (Drosophila) |
| Gene Summary | Klhl12 serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. It negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. |
| Alternative Names | C3ip1 MGC93127 |
| Molecular Weight(MW) | 62kDa |
| Sequence | 568 amino acids |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
