| Product Name | Rabbit anti-UTX polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DKFZp686A03225, MGC141941, UTX, bA386N14.2, KABUK2 |
| Immunogen | The immunogen for anti-UTX antibody: synthetic peptide directed towards the N terminal of human UTX |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanPigZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | UTX |
|---|---|
| Gene Synonyms | DKFZp686A03225 MGC141941 UTX bA386N14.2 KABUK2 |
| Gene Full Name | Lysine (K)-specific demethylase 6A |
| Gene Summary | UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A. |
| Alternative Names | DKFZp686A03225 MGC141941 UTX bA386N14.2 KABUK2 |
| Molecular Weight(MW) | 154kDa |
| Sequence | 1401 amino acids |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM109252