| Gene Symbol |
ADARB1
|
| Gene Synonyms |
ADAR2 ADAR2a ADAR2a-L1 ADAR2a-L2 ADAR2a-L3 ADAR2b ADAR2d ADAR2g DRABA2 DRADA2 RED1 |
| Gene Full Name |
Adenosine deaminase, RNA-specific, B1 |
| Gene Summary |
ADARB1 is an enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. |
| Alternative Names |
ADAR2 ADAR2a ADAR2a-L1 ADAR2a-L2 ADAR2a-L3 ADAR2b ADAR2d ADAR2g DRABA2 DRADA2 RED1 |
| Molecular Weight(MW) |
80kDa |
| Sequence |
729 amino acids |