| Product Name | Rabbit anti-PPP1R8 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ARD1, ARD-1, NIPP1, NIPP-1, PRO2047 |
| Immunogen | The immunogen for anti-PPP1R8 antibody: synthetic peptide directed towards the middle region of human PPP1R8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PPP1R8 |
|---|---|
| Gene Synonyms | ARD1 ARD-1 NIPP1 NIPP-1 PRO2047 |
| Gene Full Name | Protein phosphatase 1, regulatory subunit 8 |
| Gene Summary | This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. |
| Alternative Names | ARD1 ARD-1 NIPP1 NIPP-1 PRO2047 |
| Molecular Weight(MW) | 14kDa |
| Sequence | 127 amino acids |
| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
