| Product Name | Anti-Phospho-PPP1R8/ARD1 (Ser199) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser199 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PPP1R8 |
|---|---|
| Gene Synonyms | ARD1 ARD-1 NIPP1 NIPP-1 PRO2047 |
| Gene Full Name | protein phosphatase 1 regulatory subunit 8 |
| Gene Summary | This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008] |
| Alternative Names | Activator of RNA decay ARD 1 ARD-1 ARD1 Homolog of E.coli RNase E NIPP 1 NIPP-1 NIPP1 Nuclear inhibitor of protein phosphatase 1 nuclear inhibitor of protein phosphatase-1 alpha Nuclear subunit of PP1 PP1R8_HUMAN PPP1R8 PRO2047 Protein phosphatase 1 regulatory inhibitor subunit 8 Protein phosphatase 1 regulatory subunit 8 RNase E RNase E E. coli homolog of |
| Molecular Weight(MW) | 38 kDa |
| Cellular Localization | Cytoplasm, Nucleus, Spliceosome. |
| SwissProt ID | Q12972 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
