| Product Name | Rabbit anti-EIF2S1 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A |
| Immunogen | The immunogen for anti-EIF2S1 antibody: synthetic peptide directed towards the C terminal of human EIF2S1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | DogGoatHumanMouseZebra Fish |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | EIF2S1 |
|---|---|
| Gene Synonyms | EIF-2 EIF-2A EIF-2alpha EIF2 EIF2A |
| Gene Full Name | Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa |
| Gene Summary | The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD), and gamma (52 kD). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha.The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987).[supplied by OMIM]. |
| Alternative Names | EIF-2 EIF-2A EIF-2alpha EIF2 EIF2A |
| Molecular Weight(MW) | 35kDa |
| Sequence | 315 amino acids |
| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM109849