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RBMXL2 antibody - middle region

Catalog Number:OM110039
OM110039
Discount Price
OM110039-100ul
1~2 Week
100ul
OM110039-50ul
50ul
OM110039-20ul
20ul
1~2 Week
Product Profile
Product Name RBMXL2 antibody - middle region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-RBMXL2 antibody: synthetic peptide directed towards the middle region of human RBMXL2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
Species Reactivity Mouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol RBMXL2
Gene Synonyms HNRNPG-T
HNRPGT
HNRNPGT
Gene Full Name RNA binding motif protein, X-linked-like 2
Gene Summary The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2215 AC100875.3 67063-69277 c
Alternative Names HNRNPG-T
HNRPGT
HNRNPGT
Molecular Weight(MW) 43kDa
Sequence 392 amino acids
Database Links
Entrez Gene 27288
SwissProt ID O75526
Protein Accession NP_055284
Application

Western blot

0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 293T cell lysate
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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