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Rabbit anti-GNB1L polyclonal antibody - C-terminal region

Catalog Number:OM110321
OM110321
Discount Price
OM110321-100ul
1~2 Week
100ul
OM110321-50ul
50ul
OM110321-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-GNB1L polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Antigen Alias GY2, FKSG1, WDR14, WDVCF, DGCRK3
Immunogen The immunogen for anti-GNB1L antibody: synthetic peptide directed towards the C terminal of human GNB1L
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity Guinea PigHumanMouseRabbitRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol GNB1L
Gene Synonyms GY2
FKSG1
WDR14
WDVCF
DGCRK3
Gene Full Name Guanine nucleotide binding protein (G protein), beta polypeptide 1-like
Gene Summary GNB1L is a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. Therefore, this gene may contribute to the etiology of those disorders.This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders.
Alternative Names GY2
FKSG1
WDR14
WDVCF
DGCRK3
Molecular Weight(MW) 36kDa
Sequence 327 amino acids
Database Links
Entrez Gene 54584
SwissProt ID Q9BYB4
Protein Accession NP_443730
Application

Western blot

Host: Rabbit Target Name:GNB1L Sample Tissue:JurkatLane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration:2.5ug/mL Peptide Concentration: 2.0ug/mL Lysate Quantity: 25ug/lane Gel Concentration: 12%

Western blot

2.5ug/mlPositive Control: Jurkat cell lysate
Application Notes WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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