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ALDOB antibody - middle region

Catalog Number:OM110362
OM110362
Discount Price
OM110362-100ul
1~2 Week
100ul
OM110362-50ul
50ul
OM110362-20ul
20ul
1~2 Week
Product Profile
Product Name ALDOB antibody - middle region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-ALDOB antibody: synthetic peptide directed towards the middle region of human ALDOB
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
Species Reactivity Bovine,Horse,Human,Mouse,Pig,Rabbit,Rat,Sheep
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ALDOB
Gene Synonyms ALDB
ALDO2
Gene Full Name Aldolase B, fructose-bisphosphate
Gene Summary Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13 ) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names ALDB
ALDO2
Molecular Weight(MW) 39kDa
Sequence 364 amino acids
Database Links
Entrez Gene 229
SwissProt ID P05062
Protein Accession NP_000026
Application

Western blot

Host: Rabbit
Target Name: ALDOB
Sample Tissue: Human Fetal Liver
Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Live
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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