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Rabbit anti-HRG polyclonal antibody - middle region

Catalog Number:OM110373
OM110373
Discount Price
OM110373-100ul
1~2 Week
100ul
OM110373-50ul
50ul
OM110373-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-HRG polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias DKFZp779H1622, HPRG, HRGP
Immunogen The immunogen for anti-HRG antibody: synthetic peptide directed towards the middle region of human HRG
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity HumanRabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol HRG
Gene Synonyms DKFZp779H1622
HPRG
HRGP
Gene Full Name Histidine-rich glycoprotein
Gene Summary This histidine-rich glycoprotein(HRG) contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names DKFZp779H1622
HPRG
HRGP
Molecular Weight(MW) 58kDa
Sequence 525 amino acids
Database Links
Entrez Gene 3273
SwissProt ID P04196
Protein Accession NP_000403
Application

Western blot

Host: Rabbit Target Name: HIRIP3 Sample Tissue: 293T Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate

Western blot

Host: Rabbit Target Name: FAM46C Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0ug/ml
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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