Immunofluorescence
NmuFG| Product Name | MUC1 Antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for Anti-MUC1 antibody is: synthetic peptide directed towards the C-terminal region of Human MUC1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MUC1 |
|---|---|
| Gene Synonyms | CD227 EMA H23AG KL-6 MAM6 PEM PEMT PUM MUC-1 MUC-1/X MUC1/ZD MUC-1/SEC |
| Gene Summary | This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants. |
| Alternative Names | CD227 EMA H23AG KL-6 MAM6 PEM PEMT PUM MUC-1 MUC-1/X MUC1/ZD MUC-1/SEC |
| Molecular Weight(MW) | 14kDa |
| Sequence | 158 amino acids |
| Entrez Gene | 4582 |
|---|---|
| SwissProt ID | Q7Z538 |
| Protein Accession | NP_001037858 |
Immunofluorescence
NmuFG| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
