Immunohistochemical
Human stomachPrimary Antibody Dilution :Immunohistochemical
Pig stomachPrimary Antibody Dilution :Western blot
0.2-1 ug/ml| Product Name | MUC1 antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-MUC1 antibody: synthetic peptide directed towards the middle region of human MUC1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Bovine,Goat,Human,Mouse,Pig,Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MUC1 |
|---|---|
| Gene Synonyms | CD227 EMA H23AG MAM6 PEM PEMT PUM KL-6 MUC-1 MUC-1/X MUC1/ZD MUC-1/SEC |
| Gene Full Name | Mucin 1, cell surface associated |
| Gene Summary | MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. |
| Alternative Names | CD227 EMA H23AG MAM6 PEM PEMT PUM KL-6 MUC-1 MUC-1/X MUC1/ZD MUC-1/SEC |
| Molecular Weight(MW) | 14kDa |
| Sequence | 159 amino acids |
| Entrez Gene | 4582 |
|---|---|
| SwissProt ID | Q7Z550 |
| Protein Accession | NP_001037857 |
Immunohistochemical
Human stomachPrimary Antibody Dilution :
Immunohistochemical
Pig stomachPrimary Antibody Dilution :
Western blot
0.2-1 ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
