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Rabbit anti-CYP2C19 polyclonal antibody - middle region
Catalog Number:OM110601
OM110601
Discount Price
OM110601-100ul
1~2 Week
100ul
OM110601-50ul
50ul
OM110601-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-CYP2C19 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias CPCJ, CYP 2C, CYP2C, P450C2C, P450IIC19
Immunogen The immunogen for anti-CYP2C19 antibody: synthetic peptide directed towards the middle region of human CYP2C19
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineHumanSheep
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CYP2C19
Gene Synonyms CPCJ
CYP 2C
CYP2C
P450C2C
P450IIC19
Gene Full Name Cytochrome P450, family 2, subfamily C, polypeptide 19
Gene Summary CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names CPCJ
CYP 2C
CYP2C
P450C2C
P450IIC19
Molecular Weight(MW) 56kDa
Sequence 490 amino acids
Database Links
Entrez Gene 1557
SwissProt ID P33261
Protein Accession NP_000760
Application

Western blot

Host: Rabbit Target Name: NOP56 Sample Tissue: Human Fetal Muscle Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: WT1 Sample Tissue: 721_B Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Placenta
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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