Western blot
RabbitTarget Name: Dkk4Antibody Dilution: 1.0ug/mlSample Tissue: Mouse Pancreas| Product Name | Rabbit anti-Dkk4 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Dkk-4, MGC25705 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | MouseHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Dkk4 |
|---|---|
| Gene Synonyms | Dkk-4 MGC25705 |
| Gene Full Name | Dickkopf homolog 4 (Xenopus laevis) |
| Gene Summary | Dkk4 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. |
| Alternative Names | Dkk-4 MGC25705 |
| Molecular Weight(MW) | 24kDa |
| Sequence | 221 amino acids |
Western blot
RabbitTarget Name: Dkk4Antibody Dilution: 1.0ug/mlSample Tissue: Mouse Pancreas| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
