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Rabbit anti-CALD1 polyclonal antibody - middle region

Catalog Number:OM111018
OM111018
Discount Price
OM111018-100ul
1~2 Week
100ul
OM111018-50ul
50ul
OM111018-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-CALD1 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias CDM, H-CAD, L-CAD, MGC21352, NAG22, HCAD, LCAD
Immunogen The immunogen for anti-CALD1 antibody: synthetic peptide directed towards the middle region of human CALD1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CALD1
Gene Synonyms CDM
H-CAD
L-CAD
MGC21352
NAG22
HCAD
LCAD
Gene Full Name Caldesmon 1
Gene Summary CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alternative Names CDM
H-CAD
L-CAD
MGC21352
NAG22
HCAD
LCAD
Molecular Weight(MW) 63kDa
Sequence 538 amino acids
Database Links
Entrez Gene 800
SwissProt ID Q05682
Protein Accession NP_004333
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Transfected 293T
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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