Western blot
1 ug/mlPositive Control: MCF-7 whole cell lysates| Product Name | Rabbit anti-LIN7C polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FLJ11215, LIN-7-C, LIN-7C, MALS-3, VELI3, MALS3 |
| Immunogen | The immunogen for anti-LIN7C antibody: synthetic peptide directed towards the middle region of human LIN7C |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHumanMouseRabbitRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LIN7C |
|---|---|
| Gene Synonyms | FLJ11215 LIN-7-C LIN-7C MALS-3 VELI3 MALS3 |
| Gene Full Name | Lin-7 homolog C (C. elegans) |
| Gene Summary | LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. It forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. LIN7C ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. It is also required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. |
| Alternative Names | FLJ11215 LIN-7-C LIN-7C MALS-3 VELI3 MALS3 |
| Molecular Weight(MW) | 22kDa |
| Sequence | 197 amino acids |
Western blot
1 ug/mlPositive Control: MCF-7 whole cell lysates| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
