Ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)
Gene Summary
Ube2g1 accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro Ube2g1 catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Ube2g1 may be involved in degradation of muscle-specific proteins and mediates polyubiquitination of CYP3A4.