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Rabbit anti-WWP1 polyclonal antibody - N-terminal region

Catalog Number:OM111187
OM111187
Discount Price
OM111187-100ul
1~2 Week
100ul
OM111187-50ul
50ul
OM111187-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-WWP1 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias AIP5, DKFZp434D2111, Tiul1, hSDRP1
Immunogen The immunogen for anti-WWP1 antibody: synthetic peptide directed towards the N terminal of human WWP1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol WWP1
Gene Synonyms WWP1
Gene Full Name WW domain containing E3 ubiquitin protein ligase 1
Gene Summary WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. WWP1 is a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. WWP1 belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes.WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names AIP5
DKFZp434D2111
Tiul1
hSDRP1
Molecular Weight(MW) 105kDa
Sequence 922 amino acids
Database Links
Entrez Gene 11059
SwissProt ID Q9H0M0
Protein Accession NP_008944
Application

Application

Rabbit Anti-WWP1 Antibody Catalog Number: Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue Observed Staining: Nuclear in pinealocytes Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec

Application

WB Suggested Anti-WWP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysateWWP1 is supported by BioGPS gene expression data to be expressed in HEK293T
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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