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Rabbit anti-FBXW2 polyclonal antibody - middle region

Catalog Number:OM111194
OM111194
Discount Price
OM111194-100ul
1~2 Week
100ul
OM111194-50ul
50ul
OM111194-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-FBXW2 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias FBW2, Fwd2, MGC117371, Md6
Immunogen The immunogen for anti-FBXW2 antibody: synthetic peptide directed towards the middle region of human FBXW2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHorseHumanMousePigRabbitRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol FBXW2
Gene Synonyms FBW2
Fwd2
MGC117371
Md6
Gene Full Name F-box and WD repeat domain containing 2
Gene Summary F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. FBXW2 is the second identified member of the F-box family and contains multiple WD-40 repeats.F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
Alternative Names FBW2
Fwd2
MGC117371
Md6
Molecular Weight(MW) 51kDa
Sequence 454 amino acids
Database Links
Entrez Gene 26190
SwissProt ID Q9UKT8
Protein Accession NP_036296
Application

Western blot

Host: Rabbit Target Name: CHAD Sample Tissue: Human Adult Placenta Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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