Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate| Product Name | Rabbit anti-UBR2 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C6orf133, DKFZp686C08114, KIAA0349, MGC71112, RP3-392M17.3, bA49A4.1, dJ242G1.1, dJ392M17.3 |
| Immunogen | The immunogen for anti-UBR2 antibody: synthetic peptide directed towards the C terminal of human UBR2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMousePigRabbitRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | UBR2 |
|---|---|
| Gene Synonyms | C6orf133 DKFZp686C08114 KIAA0349 MGC71112 RP3-392M17.3 bA49A4.1 dJ242G1.1 dJ392M17.3 |
| Gene Full Name | Ubiquitin protein ligase E3 component n-recognin 2 |
| Gene Summary | Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron.Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM]. |
| Alternative Names | C6orf133 DKFZp686C08114 KIAA0349 MGC71112 RP3-392M17.3 bA49A4.1 dJ242G1.1 dJ392M17.3 |
| Molecular Weight(MW) | 200kDa |
| Sequence | 1755 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
