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LECT1 antibody - N-terminal region

Catalog Number:OM111859
OM111859
Discount Price
OM111859-100ul
1~2 Week
100ul
OM111859-50ul
50ul
OM111859-20ul
20ul
1~2 Week
Product Profile
Product Name LECT1 antibody - N-terminal region
Antibody Type Primary Antibodies
Product description Immunogen Sequence comparison: Bovine: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Dog: 92%; Horse: 92%; Pig: 92%; Rabbit: 92%; Chicken: 78%
Immunogen The immunogen for anti-LECT1 antibody: synthetic peptide directed towards the N terminal of human LECT1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
Species Reactivity BovineDogHorseHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol LECT1
Gene Synonyms BRICD3
CHM-I
CHM1
MYETS1
Gene Full Name Leukocyte cell derived chemotaxin 1
Gene Summary LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The mature protein promotes chondrocyte growth and inhibits angiogenesis. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Names BRICD3
CHM-I
CHM1
MYETS1
Molecular Weight(MW) 37kDa
Sequence 334 amino acids
Database Links
Entrez Gene 11061
SwissProt ID O75829
Protein Accession NP_008946
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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