Western blot
Host: Rabbit Target Name: POMT1 Sample Tissue: MCF7 Antibody Dilution: 1.0ug/mlWestern blot
Host: Rabbit Target Name: POMT1 Sample Tissue: Jurkat Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-POMT1 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FLJ37239, LGMD2K, RT, MDDGA1, MDDGB1, MDDGC1 |
| Immunogen | The immunogen for anti-POMT1 antibody: synthetic peptide directed towards the middle region of human POMT1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineHorseHumanMousePigRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | POMT1 |
|---|---|
| Gene Synonyms | FLJ37239 LGMD2K RT MDDGA1 MDDGB1 MDDGC1 |
| Gene Full Name | Protein-O-mannosyltransferase 1 |
| Gene Summary | POMT1 is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K).O-mannosylation is an important protein modification in eukaryotes that is initiated by an evolutionarily conserved family of protein O-mannosyltransferases. POMT1 shares sequence similarity with protein O-mannosyltransferases of S. cerevisiae. In yeast, these enzymes are located in the endoplasmic reticulum (ER) and are required for cell integrity and cell wall rigidity. POMT1 also shows similarity to the Drosophila 'rotated abdomen' (rt) gene, which when mutated causes defects in myogenesis and muscle structure.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-42 DB154785.1 1-42 43-2420 AK074874.1 1-2378 2421-2617 BF984005.1 438-634 2618-3080 AL358781.19 127610-128072 |
| Alternative Names | FLJ37239 LGMD2K RT MDDGA1 MDDGB1 MDDGC1 |
| Molecular Weight(MW) | 82kDa |
| Sequence | 725 amino acids |
| Entrez Gene | 10585 |
|---|---|
| SwissProt ID | B3KQG0 |
| Protein Accession | NP_001070833 |
Western blot
Host: Rabbit Target Name: POMT1 Sample Tissue: MCF7 Antibody Dilution: 1.0ug/ml
Western blot
Host: Rabbit Target Name: POMT1 Sample Tissue: Jurkat Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
