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Rabbit anti-ACVR2B polyclonal antibody - middle region

Catalog Number:OM112014
OM112014
Discount Price
OM112014-100ul
1~2 Week
100ul
OM112014-50ul
50ul
OM112014-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-ACVR2B polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias ACTRIIB, ActR-IIB, MGC116908, HTX4
Immunogen The immunogen for anti-ACVR2B antibody: synthetic peptide directed towards the middle region of human ACVR2B
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHorseHumanPigRatSheepZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ACVR2B
Gene Synonyms ACTRIIB
ActR-IIB
MGC116908
HTX4
Gene Full Name Activin A receptor, type IIB
Gene Summary Activin receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. ACVR2B is activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Alternative Names ACTRIIB
ActR-IIB
MGC116908
HTX4
Molecular Weight(MW) 58kDa
Sequence 512 amino acids
Database Links
Entrez Gene 93
SwissProt ID Q13705
Protein Accession NP_001097
Application

Western blot

Host: Rabbit Target Name: CHAD Sample Tissue: Human Adult Placenta Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/mlPositive Control: OVCAR-3 cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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