Immunohistochemical
ImmunohistochemicalWestern blot
1 ug/mlPositive Control: Jurkat cell lysate| Product Name | Rabbit anti-SPPL2B polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IMP4, KIAA1532, MGC111084, PSL1, IMP-4 |
| Immunogen | The immunogen for anti-SPPL2B antibody: synthetic peptide directed towards the N terminal of human SPPL2B |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Bovine |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SPPL2B |
|---|---|
| Gene Synonyms | IMP4 KIAA1532 MGC111084 PSL1 IMP-4 |
| Gene Full Name | Signal peptide peptidase like 2B |
| Gene Summary | SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. |
| Alternative Names | IMP4 KIAA1532 MGC111084 PSL1 IMP-4 |
| Molecular Weight(MW) | 56kDa |
| Sequence | 511 amino acids |
| Entrez Gene | 56928 |
|---|---|
| SwissProt ID | Q8TCT7-4 |
| Protein Accession | NP_001070706 |
Immunohistochemical
Immunohistochemical
Western blot
1 ug/mlPositive Control: Jurkat cell lysate| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
