Western blot
5.0ug/mlPositive Control: Jurkat cell lysate| Product Name | Rabbit anti-IL10RA polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDW210A, HIL-10R, IL-10R1, IL10R, CD210, CD210a |
| Immunogen | The immunogen for anti-IL10RA antibody: synthetic peptide directed towards the N terminal of human IL10RA |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanPig |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | IL10RA |
|---|---|
| Gene Synonyms | CDW210A HIL-10R IL-10R1 IL10R CD210 CD210a |
| Gene Full Name | Interleukin 10 receptor, alpha |
| Gene Summary | IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. |
| Alternative Names | CDW210A HIL-10R IL-10R1 IL10R CD210 CD210a |
| Molecular Weight(MW) | 61kDa |
| Sequence | 578 amino acids |
Western blot
5.0ug/mlPositive Control: Jurkat cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
