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Anti-Phospho-IL-10R alpha (Tyr496) antibody

Catalog Number:OM682239
OM682239
Discount Price
OM682239-100ul
100ul
Product Profile
Product Name Anti-Phospho-IL-10R alpha (Tyr496) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Tyr496
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol IL10RA
Gene Synonyms CD210
IL10R
CD210a
CDW210A
HIL-10R
IL-10R1
Gene Full Name interleukin 10 receptor subunit alpha
Gene Summary The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
Alternative Names CD210 antibody
CDw210a antibody
CDw210a antigen antibody
HIL 10R antibody
HIL10R antibody
I10R1_HUMAN antibody
IL 10R 1 antibody
IL 10R A antibody
IL 10R antibody
IL 10R1 antibody
IL-10 receptor subunit alpha antibody
IL-10R subunit 1 antibody
IL-10R subunit alpha antibody
IL-10R1 antibody
IL-10RA antibody
IL10R antibody
IL10R1 antibody
IL10RA antibody
Interleukin 10 receptor alpha antibody
Interleukin 10 receptor alpha chain antibody
Interleukin-10 receptor subunit 1 antibody
Interleukin-10 receptor subunit alpha antibody
Molecular Weight(MW) 63 kDa
Cellular Localization Cell membrane,Cytoplasm,Membrane.
Database Links
SwissProt ID Q13651
Application

ELISA

Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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