Immunohistochemistry
Immunohistochemistry with Human Colon lysate tissue at an antibody concentration of 5.0ug/ml using anti-DSG2 antibodyWestern blot
1 ug/mlPositive Control: Hela cell lysate| Product Name | Rabbit anti-DSG2 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ARVC10, ARVD10, CDHF5, HDGC, MGC117034, MGC117036, MGC117037, CMD1BB |
| Immunogen | The immunogen for anti-DSG2 antibody: synthetic peptide directed towards the N terminal of human DSG2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineGuinea PigHorseHumanMouseRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DSG2 |
|---|---|
| Gene Synonyms | ARVC10 ARVD10 CDHF5 HDGC MGC117034 MGC117036 MGC117037 CMD1BB |
| Gene Full Name | Desmoglein 2 |
| Gene Summary | Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. DSG2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Alternative Names | ARVC10 ARVD10 CDHF5 HDGC MGC117034 MGC117036 MGC117037 CMD1BB |
| Molecular Weight(MW) | 114kDa |
| Sequence | 1118 amino acids |
Immunohistochemistry
Immunohistochemistry with Human Colon lysate tissue at an antibody concentration of 5.0ug/ml using anti-DSG2 antibody
Western blot
1 ug/mlPositive Control: Hela cell lysate| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
