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Rabbit anti-STIM1 polyclonal antibody - middle region

Catalog Number:OM112114
OM112114
Discount Price
OM112114-100ul
1~2 Week
100ul
OM112114-50ul
50ul
OM112114-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-STIM1 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias D11S4896E, GOK, STIM1L
Immunogen The immunogen for anti-STIM1 antibody: synthetic peptide directed towards the middle region of human STIM1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHorseHumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol STIM1
Gene Synonyms D11S4896E
GOK
STIM1L
Gene Full Name Stromal interaction molecule 1
Gene Summary This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.
Alternative Names D11S4896E
GOK
STIM1L
Molecular Weight(MW) 75kDa
Sequence 685 amino acids
Database Links
Entrez Gene 6786
SwissProt ID Q13586
Protein Accession NP_003147
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:12500Positive Control: PANC1 cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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