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Rabbit anti-TGFB2 polyclonal antibody - middle region

Catalog Number:OM112129
OM112129
Discount Price
OM112129-100ul
1~2 Week
100ul
OM112129-50ul
50ul
OM112129-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-TGFB2 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias MGC116892, TGF-beta2
Immunogen The immunogen for anti-TGFB2 antibody: synthetic peptide directed towards the middle region of human TGFB2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHumanMousePigRabbitRatSheepZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol TGFB2
Gene Synonyms MGC116892
TGF-beta2
Gene Full Name Transforming growth factor, beta 2
Gene Summary This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alternative Names MGC116892
TGF-beta2
Molecular Weight(MW) 46kDa
Sequence 414 amino acids
Database Links
Entrez Gene 7042
SwissProt ID P61812
Protein Accession NP_003229
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: NCI-H226 cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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