| Product Name | Anti-TGFB2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | TGFB2 |
|---|---|
| Gene Synonyms | ARVD ARVD1 CAEND1 CAEND2 CED DPD1 G-TSF IBDIMDE LAP LDS4 LDS5 MGF RNHF TGF-beta-2 TGF-beta-3 TGF-beta1 TGF-beta2 TGF-beta3 TGF-beta4 TGFB Tgfb-1 Tgfb-2 Tgfb-3 TGFB4 TGFbeta TGFbeta1 |
| Gene Full Name | transforming growth factor beta 2 |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016] |
| Alternative Names | BSC-1 cell growth inhibitor cetermin glioblastoma-derived T-cell suppressor factor latency-associated peptide milk growth factor polyergin prepro-transforming growth factor beta-1 prepro-transforming growth factor beta-2 prepro-transforming growth factor beta-3 tgf beta 1 TGF beta 3 tgf beta1 TGF beta2 TGF-beta precursor TGF-beta-1 TGF-beta-2 tissue growth factor-beta4 Transforming growth factor transforming growth factor beta 4 transforming growth factor beta precursor transforming growth factor beta-3 (TGF beta-3) precursor (start site 611 could be 368 or 477) transforming growth factor beta1 transforming growth factor beta 1 (Camurati-Engelmann disease) transforming growth factor-beta-1 precursor transforming growth factor-beta-2 precursor transforming growth factor-beta2 transforming growth factor-beta3 |
| Molecular Weight(MW) | 47kDa |
| Source | Rabbit |
| Cellular Localization | Secreted, extracellular space, extracellular matrix;Secreted |
| SwissProt ID | P61812 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
