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Rabbit anti-GALNT4 polyclonal antibody - middle region

Catalog Number:OM112141
OM112141
Discount Price
OM112141-100ul
1~2 Week
100ul
OM112141-50ul
50ul
OM112141-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-GALNT4 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias GALNAC-T4, GalNAcT4, GALNACT4
Immunogen The immunogen for anti-GALNT4 antibody: synthetic peptide directed towards the middle region of human GALNT4
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineHorseHumanRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol GALNT4
Gene Synonyms GALNAC-T4
GalNAcT4
GALNACT4
Gene Full Name UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
Gene Summary GALNT4 is a member of the UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule.This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon.
Alternative Names GALNAC-T4
GalNAcT4
GALNACT4
Molecular Weight(MW) 67kDa
Sequence 578 amino acids
Database Links
Entrez Gene 8693
SwissProt ID Q8N4A0
Protein Accession NP_003765
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Stomach
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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