| Gene Symbol |
C21orf33
|
| Gene Synonyms |
D21S2048E ES1 GT335 HES1 KNP-I KNPH KNPI |
| Gene Full Name |
Chromosome 21 open reading frame 33 |
| Gene Summary |
C21orf33 inhibits both estrogen- and heregulin-beta1-stimulated growth of breast cancer cells, and further suggests that growth inhibition induced in these cells by all-trans retinoic acid occurs via HES-1-mediated downregulation of E2F-1 expression. C21orf33 may also be a candidate protein involved in the pathogenesis of the brain deficit in DS. |
| Alternative Names |
D21S2048E ES1 GT335 HES1 KNP-I KNPH KNPI |
| Molecular Weight(MW) |
21kDa |
| Sequence |
237 amino acids |