Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Transfected 293T| Product Name | Rabbit anti-RMI1 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BLAP75, C9orf76, FLJ12888, RP11-346I8.1 |
| Immunogen | The immunogen for anti-RMI1 antibody: synthetic peptide directed towards the N terminal of human RMI1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RMI1 |
|---|---|
| Gene Synonyms | BLAP75 C9orf76 FLJ12888 RP11-346I8.1 |
| Gene Full Name | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae) |
| Gene Summary | RMI1 is an essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. RMI1 promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. RMI1 is required for BLM phosphorylation during mitosis. Within the BLM complex, RMI1 is required for BLM and TOP3A stability.RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006 [PubMed 16595695]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-136 BP327553.1 1-136 137-885 DN997105.1 9-757 886-2740 AL732446.4 14777-16631 2741-3508 BC039999.2 2566-3333 |
| Alternative Names | BLAP75 C9orf76 FLJ12888 RP11-346I8.1 |
| Molecular Weight(MW) | 70kDa |
| Sequence | 625 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Transfected 293T| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
