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Rabbit anti-CDH12 polyclonal antibody - middle region

Catalog Number:OM112509
OM112509
Discount Price
OM112509-100ul
1~2 Week
100ul
OM112509-50ul
50ul
OM112509-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-CDH12 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias CDHB, FLJ34857
Immunogen The immunogen for anti-CDH12 antibody: synthetic peptide directed towards the middle region of human CDH12
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity DogHorseHumanPigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CDH12
Gene Synonyms CDHB
FLJ34857
Gene Full Name Cadherin 12, type 2 (N-cadherin 2)
Gene Summary CDH12 belongs to the protocadherin protein family, a subfamily of the cadherin superfamily. It consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
Alternative Names CDHB
FLJ34857
Molecular Weight(MW) 82kDa
Sequence 794 amino acids
Database Links
Entrez Gene 1010
SwissProt ID P55289
Protein Accession NP_004052
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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