| Product Name | Rabbit anti-ZMPSTE24 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FACE-1, FACE1, FLJ14968, STE24, Ste24p, HGPS, PRO1 |
| Immunogen | The immunogen for anti-ZMPSTE24 antibody: synthetic peptide directed towards the N terminal of human ZMPSTE24 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseMouseRabbitRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ZMPSTE24 |
|---|---|
| Gene Synonyms | FACE-1 FACE1 FLJ14968 STE24 Ste24p HGPS PRO1 |
| Gene Full Name | Zinc metallopeptidase STE24 homolog (S. cerevisiae) |
| Gene Summary | ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins. |
| Alternative Names | FACE-1 FACE1 FLJ14968 STE24 Ste24p HGPS PRO1 |
| Molecular Weight(MW) | 55kDa |
| Sequence | 475 amino acids |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
