Immunohistochemical
TestisImmunofluorescence
ImmunofluorescenceImmunohistochemical
AdrenalWestern blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Live| Product Name | Rabbit anti-BACE1 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ASP2, BACE, FLJ90568, HSPC104, KIAA1149 |
| Immunogen | The immunogen for anti-BACE1 antibody: synthetic peptide directed towards the N terminal of human BACE1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineGuinea PigHorseHumanMousePigRabbitRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BACE1 |
|---|---|
| Gene Synonyms | ASP2 BACE FLJ90568 HSPC104 KIAA1149 |
| Gene Full Name | Beta-site APP-cleaving enzyme 1 |
| Gene Summary | Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein. BACE1, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene. |
| Alternative Names | ASP2 BACE FLJ90568 HSPC104 KIAA1149 |
| Molecular Weight(MW) | 51kDa |
| Sequence | 501 amino acids |
Immunohistochemical
Testis
Immunofluorescence
Immunofluorescence
Immunohistochemical
Adrenal
Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Live| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
