| Product Name | Anti-BACE1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | BACE1 |
|---|---|
| Gene Synonyms | ASP2 BACE HSPC104 |
| Gene Full Name | beta-secretase 1 |
| Gene Summary | This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015] |
| Alternative Names | APP beta-secretase asp 2 ASP2 aspartyl protease 2 BACE BACE 1 BACE-1B BACE-1C BACE-1D BACE-I-432 BACEdelta7 Beta secretase beta-site amyloid beta A4 precursor protein-cleaving enzyme beta-site amyloid precursor protein cleaving enzyme 1 beta-site APP cleaving enzyme 1 beta-site APP processing enzyme beta-site APP-cleaving enzyme beta-site APP-cleaving enzyme 1 Memapsin memapsin-2 Memapsin2 membrane type aspartyl protease membrane-associated aspartic protease 2 protease transmembrane aspartic proteinase Asp2 |
| Molecular Weight(MW) | 55kDa |
| Source | Rabbit |
| Cellular Localization | Cell membrane;Golgi apparatus, trans-Golgi network;Endoplasmic reticulum;Endosome;Cell surface;Cytoplasmic vesicle membrane;Membrane raft;Lysosome;Late endosome;Early endosome;Recycling endosome;Cell projection, axon;Cell projection, dendrite |
| SwissProt ID | P56817 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
